Nonmelanoma histiocytoma skin cancer (nmsc) signs, symptoms and treatments

Skin cancer is the most common malignancy in the united histiocytoma dog removal cost states and represents approximately 35‐45% of all cancers in caucasians, 4‐5% in hispanics, and 1‐4% in asians , asian indians and african‐americans.1‐3 although skin cancer occurs less frequently in dark‐skinned people, it is often associated with greater morbidity and mortality compared histiocytoma dog removal cost to light‐skinned individuals.3‐4 therefore, it is important for people of all races to be histiocytoma dog removal cost aware of the risks of both melanoma‐‐the most deadly type of skin cancer‐‐and other more common types which are collectively termed non‐melanoma skin cancer (NMSC). Squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) are the two most common forms of NMSC.

SCC accounts for approximately 20% of all skin cancers and about 75% of all deaths due to skin cancer, excluding melanoma.5,6 it is the most common skin cancer in african-americans and asian indians and the second most common skin histiocytoma dog removal cost cancer in hispanics, asians (chinese and japanese) and caucasians.3 BCC is the most common skin cancer in hispanics, chinese and japanese asians, and caucasians.3 though BCC can be locally destructive, it rarely metastasizes (spreads).

NMSC has many causes. Ultraviolet (UV) radiation from sunlight, scarring processes, chronic injury, and depressed immune system (e.G., after organ transplantation) all contribute to the development of NMSC. UV radiation is the primary cause of both SCC and histiocytoma dog removal cost BCC in caucasians, hispanics, and asians. 3 however, the most important predisposing factors for the development of SCC histiocytoma dog removal cost in african-americans are chronic scarring, trauma, and inflammation (e.G., burns, non-healing leg ulcers, skin lupus), not sun-exposure.7 the main risk factor for BCC in all races histiocytoma dog removal cost is UV radiation.8 darker skin color does provide a protective effect, however, as BCC is more common in lighter skinned- versus darker-skinned african-americans. 7

NMSC can look many different ways. Both SCC and BCC may be without symptoms, or grow slowly over time with associated pain or spontaneous histiocytoma dog removal cost bleeding. In dark-skinned individuals, SCC tends to occur in skin that is unexposed such histiocytoma dog removal cost as the legs, anus, and genitals whereas in lighter-skinned people, sun-exposed skin is the most common site. 8 bccs most often occur in the head and neck histiocytoma dog removal cost regions in all races. These most commonly present as painless, shiny, solitary bumps. Like sccs, these may have a tendency to bleed easily. In people of color, more than 50% of bccs have pigment (dark color), as opposed to only 5% in caucasians. 3,9 if any new lesion is painful, bleeding, growing, changing, or is otherwise concerning to you, it should be evaluated by your dermatologist.

In addition to surgical techniques, topical immunomodulators, such as imiquimod, have gained recent FDA approval for treatment of thin NMSC. These treat the skin cancer by boosting the local immune histiocytoma dog removal cost system to kill the tumor. Another option is photodynamic therapy (PDT), which is a combination of a topical photosensitizing cream and histiocytoma dog removal cost a specialized light. Additionally, 5-fluorouracil cream (a chemotherapeutic agent) can be used to treat NMSC. All topical options have the benefit of treating NMSC with histiocytoma dog removal cost less risk for scarring. However, unlike MMS, excision or EDC, complete cure cannot be ascertained and topical agents cannot be histiocytoma dog removal cost used on large or deep tumors. Overall the cure rates are lower and recurrences more common histiocytoma dog removal cost than with surgical treatments. 11 lastly, radiation is used on large or high-risk tumors that cannot be completely treated with surgery.

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